Small interfering RNAs (siRNAs) are short, double-stranded RNA molecules that can target and degradate specific complementary mRNAs. The target gene-specific degradation is an effective means of gene suppression. BioVision's GeneBlocker pGB siRNA expression vectors are designed to provide efficient suppression of a target gene in cultured mammalian cells and in vivo. The pGB vector has been optimized for suppressing expression of target genes using the human U6 promotor (a RNA polymerase III promotor) which generates large amounts of siRNA in mammalian cells. The pGB vector provides neomycin resistance marker for the selection of stable cell lines, permitting long term suppression of the target gene. BioVision offers siRNA vectors targeting to important Apoptosis genes. The negative control siRNA vector and pGB cloning vector for cloning in your own insert are also available.

 


 
   

 
siRNA Cloning Vector      
Product Cat. # Size Data Sheet
GeneBlockerTM siRNA Cloning Vector (pGB) 9500-1 1 each Product Data Sheet

 
siRNA Negative Control Vector      
Product Cat. # Size Data Sheet
GeneBlockerTM Negative Control siRNA Vector (pGB-Control) 9500C-1 20 ug Product Data Sheet

 
AIF siRNA Vectors      
Product Cat. # Size Data Sheet
GeneBlockerTM AIF siRNA Vector Mix (pGB-AIF) 9511-20 20 ug Product Data Sheet
GeneBlockerTM AIF siRNA Vector Mix (pGB-AIF) 9511-60 60 ug Product Data Sheet

 
Bcl-2 siRNA Vectors      
Product Cat. # Size Data Sheet
GeneBlockerTM BAD siRNA Vector Mix (pGB-BAD) 9512-20 20 ug Product Data Sheet
GeneBlockerTM BAD siRNA Vector Mix (pGB-BAD) 9512-60 60 ug Product Data Sheet
GeneBlockerTM BAX siRNA Vector Mix (pGB-BAX) 9513-20 20 ug Product Data Sheet
GeneBlockerTM BAX siRNA Vector Mix (pGB-BAX) 9513-60 60 ug Product Data Sheet
GeneBlockerTM BCL-2 siRNA Vector Mix (pGB-BCL-2) 9514-20 20 ug Product Data Sheet
GeneBlockerTM BCL-2 siRNA Vector Mix (pGB-BCL-2) 9514-60 60 ug Product Data Sheet
GeneBlockerTM BID siRNA Vector Mix (pGB-BID) 9515-20 20 ug Product Data Sheet
GeneBlockerTM BID siRNA Vector Mix (pGB-BID) 9515-60 60 ug Product Data Sheet

 
Caspase Family siRNA Vectors      
Product Cat. # Size Data Sheet
GeneBlockerTM Caspase-1 siRNA Vector (pGB-Casp-1) 9501-1 20 ug Product Data Sheet
GeneBlockerTM Caspase-3 siRNA Vector (pGB-Casp-3) 9503-1 20 ug Product Data Sheet
GeneBlockerTM Caspase-8 siRNA Vector (pGB-Casp-8) 9508-1 20 ug Product Data Sheet
GeneBlockerTM Caspase-9 siRNA Vector (pGB-Casp-9) 9509-1 20 ug Product Data Sheet

 
Heat Shock Protein 90 siRNA Vectors      
Product Cat. # Size Data Sheet
GeneBlockerTM HSP90 siRNA Vector Mix (pGB-HSP90) 9518-20 20 ug Product Data Sheet
GeneBlockerTM HSP90 siRNA Vector Mix (pGB-HSP90) 9518-60 60 ug Product Data Sheet

 
cIAP Family siRNA Vectors      
Product Cat. # Size Data Sheet
GeneBlockerTM CIAP1 siRNA Vector Mix (pGB-CIAP1) 9516-20 20 ug Product Data Sheet
GeneBlockerTM CIAP1 siRNA Vector Mix (pGB-CIAP1) 9516-60 60 ug Product Data Sheet
GeneBlockerTM CIAP2 siRNA Vector Mix (pGB-CIAP2) 9517-20 20 ug Product Data Sheet
GeneBlockerTM CIAP2 siRNA Vector Mix (pGB-CIAP2) 9517-60 60 ug Product Data Sheet

Pricelist