BioVision offers high quality human, mouse, and rat recombinant active and pro-caspases that were expressed in E. coli and purified. Active caspases are useful in studying enzyme regulation and kinetics, screen caspase inhibitors, determine target substrates, and as positive controls in caspase activity assays and Western blot analyses. One unit of the active enzyme is sufficient to cleave 1 nmol of the corresponding caspase substrate per hour at 37oC and is sufficient for one caspase activity assay. Procaspase-3 & -7 are also available for studying caspase pathways.
 


Active Caspases Effectively Cleave Peptide Substrates. Activity of the active human caspase-2,-3,-6,-8 were determined by their ability to cleave the fluorometric substrate of each caspase, as indicated. The cleavage was effectively inhibited by the corresponding peptide inhibitors, as indicated.

 
Product Cat. # Size Data Sheet
Active Human Caspase-1 1081-25 25 units Product Data Sheet
Active Human Caspase-1 1081-100 100 units Product Data Sheet
Active Human Caspase-2 1082-25 25 units Product Data Sheet
Active Human Caspase-2 1082-100 100 units Product Data Sheet
Active Human Caspase-3 1083-25 25 units Product Data Sheet
Active Human Caspase-3 1083-100 100 units Product Data Sheet
Active Human Caspase-3 1083-5 5 ug Product Data Sheet
Active Human Caspase-3 1083-10 10 ug Product Data Sheet
Human Procaspase-3 1083P-5 5 ug Product Data Sheet
Active Mouse Caspase-3 1183-25 25 units Product Data Sheet
Active Mouse Caspase-3 1183-100 100 units Product Data Sheet
Mouse Pro-Caspase-3 1183P-5 5 ug Product Data Sheet
Active Rat Caspase-3 1283-25 25 units Product Data Sheet
Active Rat Caspase-3 1283-100 100 units Product Data Sheet
Active Human Caspase-4 1084-25 25 units Product Data Sheet
Active Human Caspase-4 1084-100 100 units Product Data Sheet
Active Human Caspase-5 1085-25 25 units Product Data Sheet
Active Human Caspase-5 1085-100 100 units Product Data Sheet
Active Human Caspase-6 1086-25 25 units Product Data Sheet
Active Human Caspase-6 1086-100 100 units Product Data Sheet
Active Human Caspase-7 1087-25 25 units Product Data Sheet
Active Human Caspase-7 1087-100 100 units Product Data Sheet
Active Human Caspase-8 1088-25 25 units Product Data Sheet
Active Human Caspase-8 1088-100 100 units Product Data Sheet
Active Human Caspase-9 1089-25 25 units Product Data Sheet
Active Human Caspase-9 1089-100 100 units Product Data Sheet
Rec Pro-Caspase-9 1089P-50 50 ug Product Data Sheet
Active Human Caspase-10/a 1090A-25 25 units Product Data Sheet
Active Human Caspase-10/a 1090A-100 100 units Product Data Sheet
Active Human Caspase-10/b 1090B-25 25 units Product Data Sheet
Active Human Caspase-10/b 1090B-100 100 units Product Data Sheet
Active Human Caspases, Group I
Contains active human caspase-1,-4,-5
K241-3-25 3 x 25 units Product Data Sheet
Active Human Caspases, Group II
Contains active human caspase-2,-3,-7
K242-3-25 3 x 25 units Product Data Sheet
Active Human Caspases, Group III
Contains active human caspase-6,-8,-9,-10
K243-4-25 4 x 25 units Product Data Sheet
Active Recombinant Caspase Set III
Contains active human caspase-1,-2,-3,-6,-7,-8,-9,-10
K232-8-25 8 x 25 units Product Data Sheet
Active Recombinant Caspase Set IV
Contains active human caspase-1,-2,-3,-4,-5,-6,-7,-8,-9,-10
K233-10-25 10 x 25 units Product Data Sheet

Pricelist