BioVision provides potent, ready-to-use caspase inhibitors that are synthesized using a proprietary Technology. These inhibitors are cell-permeable, nontoxic, and irreversibly bind to activated caspases to block apoptosis. For cell cultures, the 2 mM caspase inhibitors can be used at 1000X dilutions (e.g., Add 1 ml to 1 ml of culture medium). For in vivo injections, the 10 mM caspase inhibitors are provided. Caspase Inhibitor Sets in the ready-to-use form are also available, providing more convenience for researchers to study multiple apoptosis-inhibiting processes.
 
 

 
Caspase Inhibitors Effectively Inhibit Caspase Activity in Cell Culture. Apoptosis was induced in Jurkat cells with campto-thecin in the presence of various concentrations (0 - 3 mM) of caspase inhibitors as indicated. Caspase activities were analyzed using Caspase-3 (for Fig. A & C) and Caspase-8 (for Fig. B) Fluorometric Assay Kits, respectively, according to the kit instructions.

 
Product Cat. # Size Data Sheet
Caspase-1 Inhibitor, Z-YVAD-FMK 1012-100 100 ul Product Data Sheet
Caspase-1 Inhibitor, Z-YVAD-FMK 1012-20C 20 ul Product Data Sheet
Caspase-2 Inhibitor, Z-VDVAD-FMK 1073-100 100 ul Product Data Sheet
Caspase-2 Inhibitor, Z-VDVAD-FMK 1073-20C 20 ul Product Data Sheet
Caspase-3 Inhibitor, Z-DEVD-FMK 1009-100 100 ul Product Data Sheet
Caspase-3 Inhibitor, Z-DEVD-FMK 1009-20C 20 ul Product Data Sheet
Caspase-4 Inhibitor, Z-LEVD-FMK 1108-100 100 ul Product Data Sheet
Caspase-4 Inhibitor, Z-LEVD-FMK 1108-20C 20 ul Product Data Sheet
Caspase-5 Inhibitor, Z-WEHD-FMK 1100-100 100 ul Product Data Sheet
Caspase-5 Inhibitor, Z-WEHD-FMK 1100-20C 20 ul Product Data Sheet
Caspase-6 Inhibitor, Z-VEID-FMK 1011-100 100 ul Product Data Sheet
Caspase-6 Inhibitor, Z-VEID-FMK 1011-20C 20 ul Product Data Sheet
Caspase-8 Inhibitor, Z-IETD-FMK 1064-100 100 ul Product Data Sheet
Caspase-8 Inhibitor, Z-IETD-FMK 1064-20C 20 ul Product Data Sheet
Caspase-9 Inhibitor, Z-LEHD-FMK 1074-100 100 ul Product Data Sheet
Caspase-9 Inhibitor, Z-LEHD-FMK 1074-20C 20 ul Product Data Sheet
Caspase-10 Inhibitor, Z-AEVD-FMK 1112-100 100 ul Product Data Sheet
Caspase-10 Inhibitor, Z-AEVD-FMK 1112-20C 20 ul Product Data Sheet
Caspase-12 Inhibitor, Z-ATAD-FMK 1079-100 100 ul Product Data Sheet
Caspase-12 Inhibitor, Z-ATAD-FMK 1079-20C 20 ul Product Data Sheet
Caspase-13 Inhibitor, Z-LEED-FMK 1115-100 100 ul Product Data Sheet
Caspase-13 Inhibitor, Z-LEED-FMK 1115-20C 20 ul Product Data Sheet
Caspase-Family Inhibitor, Z-VAD-FMK 1010-100 100 ul Product Data Sheet
Caspase-Family Inhibitor, Z-VAD-FMK 1010-20C 20 ul Product Data Sheet
FMK Negative Control, Z-FA-FMK 1122-100 100 ul Product Data Sheet
FMK Negative Control, Z-FA-FMK 1122-20C 20 ul Product Data Sheet
 
Caspase-Family Inhibitor Set
Contains 25 ml of Caspase-1,-3,-6,-8, & -Family Inhibitors.
K107-5-25 5 X 25ul Product Data Sheet
Caspase-Family Inhibitor Set Plus
Contains 25 ml of Caspase-1,-2,-3,-6,-8,-9 & -Family Inhibitors.
K108-7-25 7 X 25 ul Product Data Sheet
Caspase-Family Inhibitor Set III
Contains 25 ml of Caspase-1,-2,-3,-5,-6,-8,-9, & -Family Inhibitors.
K210-8-25 8 X 25 ul Product Data Sheet
Caspase-Family Inhibitor Set IV
Contains 25 ml each of the above 12 Inhibitors.
K220-12-25 12 X 25 ul Product Data Sheet

Pricelist