GENTAUR Oxidative Stress Markers

JaICA New 8-OHdG Check ELISA
8-hydroxy-2'-deoxyguanosine (8-OHdG) is a product of oxidative damaged DNA formed by hydroxy radical, singlet oxygen and direct photodynamic action.
We provide two types of 8-OHdG ELISA kits with different assay range. New 8-OHdG Check ELISA is suitable for urine and serum sample from animal and human. If you are planning to measure 8-OHdG in human serum, tissue, cultured cells, we recommend to use 'Highly Sensitive 8-OHdG Check ELISA'.

Code Product Name Quantity Price
KOG-200SE New 8-OHdG Check ELISA Kit 1x 96 well 795€
KOG-200TE New 8-OHdG Check ELISA Trial Package 1x 32 well 438€
KOG-HS10E Highly Sensitive 8-OHdG Check ELISA 1x 96 well 795€
MOG-100P Anti 8-OHdG monoclonal antibody 100 µg 975€
MOG-020P Anti 8-OHdG monoclonal antibody 20 µg 350€

Formation of 8-hydroxy-2’-deoxyguanosine (8-OhdG) by oxygen radicals.

Features:

·     Time-tested & Supported by numerous publications

·     High specificity & High quality

·     Easy operation & Speedy

·     Full technical support

 

Thiobarbituric Acid Reactive Substances

Measurement of Thiobarbituric Acid Reactive Substances (TBARS) is the gold standard for assay of oxidative stress. This rapid, easy-to-use procedure has been modified by researchers for use with many types of samples including drugs, food products and human and animal biological tissues. The OXI-TEK TBARS assay kit is a calibrated kit designed for the measurement of oxidative stress in biological samples. This assay may be used for testing antioxidants and drugs.

 

Code Product Name Quantity Price
801192 TBARS Assay Kit 160 tests 385€
801218 8-Oxo-dG Nucleoside Standard 1.0 mg 106€
801219 8-Oxo-dA Nucleoside Standard 1.0 mg 110€
801219 8-Oxo-dG*N15 Nucleoside Standard 50 pM 617€

Malondialdehyde (MDA) forms a 1:2 adduct with thiobarbituric acid; the adduct can be measured by fluorometry.

 

Features:

·     Supported by numerous publications

·     High specificity & High quality

·     Rapid & Easy procedure

·     Large samples range, almost any body fluid, tissue and cultured cells.

·     Anti-Oxidant and Drug Screening

 

Assay Designs Oxidative Stress products
ROS commonly refers to speroxide anions, hydrohen peroxide, hypohalous acid and hydroxyl radicals. ROS may lead to the oxidative damage of virtually any molecule. Degradation of proteins by free-radicals induces stress proteins which include: Heme Oxygenase-1 and -2, Superoxide Dismutase, Ubiquitin, Catalase and Glutathione peroxidase, among others. As overproduction of ROS has been associated with many diseases, these regulatory proteins have drawn great interest as potential therapeutic markers.
Code Product Name Quantity Price
907-027 Catalase Fluometric Detection Kit 500 tests 371€
900-157 SOD Colometric Activity Kit 5x 96 well 674€
900-158 Glutathione Peroxidase Activity Kit 5x 96 well 674€
900-159 Glutathione Reductase Activity Kit 5x 96 well 674€
900-160 Glutathione Detection Kit (total) 4x 96 well 466€
EKS-800 HO-1 (Human) EIA Kit 1x 96 well 750€
EKS-810A HO-1 (Rat) EIA Kit 1 x96 well 750€
917-010 Nitric Oxide (NO2/NO3) Assay Kit 2x 96 well 255€
917-020 Nitric Oxide (Total) Assay Kit 2x 96 well 255€
SPA-540E Glutathione NEM mAb (8.IGSH) 100 µg 360€
915-041 Neutrophil Myeloperoxidase pAb 100 µg 360€
SPA-895F HO-1 (Hsp32) Polyclonal Antibody 200 µg 370€
 

Features:

·     Sensitive – accurate detection of biomarkers at low level using minimal sample volume.

·     Flexible – kit and reagent formats to suit your sample type, species, and application needs.

·     Validated – qualified in-house and widely cited in peer reviewed journals.

The Nitric Oxide (NO2/NO3) Assay Kit

·     Measures nitrate and nitrite separately

·     Range - (Nitrite) 3.125 - 200 µmole/L

·     Range -  (Nitrate) 3.125 - 100 µmole/L

·     Sensitivity - (Nitrite) 0.222 µmole/L

·     Sensitivity - (Nitrate) 0.625 µmole/L

·     Species Independent

Polyclonal Antibodies

Alzheimer’s diseased brain section stained with HO-1 (Hsp32) Polyclonal antibody

 Ab Front Superoxide Dismutase ELISA Kits

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against ROS. SOD-1 is found in all eukaryotic species containing one each of Cu and Zn ion per subunit. The manganese containing enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD-3 is a heparin-binding multimer, primarily expressed in human lungs, vessel walls and airways.

Code Product Name Quantity Price
LF-EK0101 Human SOD-1 ELISA kit 1 x96 well 442
LF-EK0104 Human SOD-2 ELISA kit 1 x96 well 572€
LF-EK0107 Human SOD-3 ELISA kit 1 x96 well 572€

 

Features:

·     Very high sensitivity

·     Simple: pre-coated plate

·     Specificity: no cross-reactivity with the other human SOD forms, including SOD-4

·     Precision: %CV is within 10%

·     Accuracy: %recovery and linearity is within 95~105%

·     Room temperature incubation

·     Sample: Serum, Plasma, Cell lysate and buffer solution

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